Cortisol · Female hormones
Pregnenolone steal: when stress hijacks your hormones
Why your libido, mood and cycles collapse when cortisol takes over.
Under chronic stress, pregnenolone — the shared precursor of all your steroid hormones — is massively diverted to make cortisol, at the expense of progesterone, oestrogens and DHEA. The body picks survival over reproduction.
This exploration unpacks the pregnenolone steal, why perimenopause worsens it, and what to actually do to rebalance without blindly supplementing.
The steroid cascade
Cholesterol → pregnenolone → the hormonal crossroads.
The cortisol shunt
What stress takes before anyone else.
Perimenopause amplified
Why falling progesterone compounds the steal.
Clinical signs
Libido, sleep, mood, cycles: read the map.
Rebalance
Order of action: terrain before supplementation.
5 panels · validation exploration · sources Endocrinology 2022, Climacteric 2018
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