Hub : Genotypes
When your genes talk to your plate
Four major polymorphisms : APOE, MTHFR, DIO2, FADS1/FADS2 : shape your metabolism, brain, and thyroid. Explore each with concrete levers.
NeurologyAPOE
APOE : brain & lifestyle
The APOE polymorphism (ε2/ε3/ε4) modulates cognitive risk. Nutritional and lifestyle levers to know.
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MethylationMTHFR
MTHFR : methylation & folates
MTHFR C677T & A1298C: folate conversion, homocysteine, and methyl load.
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ThyroidDIO2
DIO2 : T4 → T3 conversion
The DIO2 rs225014 polymorphism influences peripheral T4-to-T3 conversion.
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LipidsFADS1 / FADS2
FADS1/FADS2 : omega-3 & omega-6
FADS1/FADS2 variants alter fatty-acid desaturation: implications for omega-6, DHA, EPA.
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MicrobiotaFUT1 / FUT2
FUT1/FUT2 : microbiota & vitamin B12
FUT1/FUT2 polymorphisms shape mucus fucosylation, microbiota, immunity and B12 absorption.
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