Neurofibrillary tangles
Intracellular aggregates formed by hyperphosphorylated and glycosylated Tau protein. They constitute the second hallmark lesion of Alzheimer's, appearing 15-20 years before symptoms. AGEs promote their formation.
Intracellular aggregates formed by hyperphosphorylated and glycosylated Tau protein. They constitute the second hallmark lesion of Alzheimer's, appearing 15-20 years before symptoms. AGEs promote their formation.
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