Bypass, sleeve: why it works (and why weight sometimes returns)
It's not just about stomach volume : it's a full rewiring of the gut-brain dialogue.
Bariatric surgery doesn't just shrink the stomach: it rewires neuropods, amplifies endogenous GLP-1, alters bile acids and the microbiome. These changes explain rapid weight loss : and also late relapses.
This exploration describes neuro-hormonal mechanisms (GLP-1, PYY, ghrelin), critical windows (12-24 months), the role of the microbiome and taste preference (striatal PPAR-α), and what can be naturally supported to prevent regain.
Clinical sources (LABS-2, JAMA, Cell Metabolism) · not medical advice
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