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    Nutrilexic · Digestion · Reflux & PPIs

    Reflux and PPIs: what we're not told

    Reflux is almost never an excess of acid. Long-term PPI use is almost never harmless.

    Gastro-oesophageal reflux affects roughly one in five adults in Europe. In most cases, it doesn't come from excess acid but from a lower oesophageal sphincter that closes poorly, sluggish gastric emptying or a hiatal hernia.

    PPIs bring relief within 3 days, but taken continuously for years, they impair absorption of B12, magnesium, iron and calcium, promote SIBO and increase kidney risk. This guide details the real causes, alternatives and a validated gradual tapering protocol.

    The real causes
    Sphincter, gastric emptying, hiatal hernia, abdominal pressure.
    Long-term PPIs
    B12, Mg, iron, Ca deficits. SIBO. Kidney and bone risk.
    Natural alternatives
    Weight, posture, chewing, alginate, melatonin, chewing gum.
    Tapering protocol
    The AGA 2022 schema to stop without acid rebound.

    Sources ACG 2022, AGA 2022 & 2017, HUNT cohort, JAMA Intern Med 2016

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