The sonic levers of memory.
Two sound-related pathways cross Alzheimer's research. On one side, entraining brainwaves at 40 Hz to support glymphatic clearance. On the other, music therapy — actively practised or receptively listened to — targeting anxiety, agitation and autobiographical memory. This page brings both together.
Brainwaves & Alzheimer's: the 40 Hz hypothesis
Gamma rhythms at 40 Hz activate microglia and boost glymphatic clearance of amyloid. What the GENUS trials show, what the light and sound protocols look like, and where the evidence still stands as of 2026.
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Singing, playing an instrument, guided listening — which formats have been studied in memory disorders, on which markers (anxiety, agitation, autobiographical recall) and with what magnitude of effect.
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